Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity
Fig 11
The effect of (A) host tissue Hb saturation, (B) tumor tissue Hb saturation, (C) tumor RBF and (D) percent decrease in total tumor hypoxic volume on the percent changes in the boundary hypoxic volume.
The baseline (unsupplemented) condition is depicted as the dashed line at zero. Letters labeling each data point indicate the vessel bed configuration for that artificial tumor construct. The non O2 carrying control is green, R-State PolyhHb is red, and T-State PolyhHb is blue.