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Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity

Fig 10

Changes in tumor hypoxia for the simulated PolyhHb enhanced infusion model.

Variations in the (A) tumor tissue pO₂, (B) boundary tissue pO₂, (C) hypoxic fraction, and (D) boundary hypoxic fraction for infusion of the control, 30:1 R-State PolyhHb, and 35:1 T-State PolyhHb.

doi: https://doi.org/10.1371/journal.pcbi.1008157.g010