Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity

doi:10.1371/journal.pcbi.1008157

Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity

Fig 8

Changes in tumor vascular architecture and Hb/PolyhHb concentrations for the simulated PolyhHb enhanced infusion model.

Variations in the (A) RBV, (B) RBF, (C) C_Hb,tis, (D) Hb O₂ saturation in RBC, (E) PolyhHb (HBOC) concentration, (F) PolyhHb (HBOC) O₂ saturation, (G) blood pO₂, and (H) MRO₂ for the baseline, top-load, and exchange infusion of the control, 30:1 R-State PolyhHb, and 35:1 T-State PolyhHb.

doi: https://doi.org/10.1371/journal.pcbi.1008157.g008