Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity
Fig 6
PCA biplot for principal components 1 and 2 for the analysis of the mouse model.
PC scores for tissue properties and O2 delivery for each of the simulated mouse tumor treatments for (A) principal component 1 and (C) principal component 3 as a function of principal component 2. Grouping in panel A is based on tumor vascular bed type. Grouping in panel B is based on dosing type. Ellipses are drawn around each group with 68% of the normal probability. Loading plots relating how each parameter influences the corresponding principal component is shown for (B) principal component 1 and (D) principal component 3 as a function of principal component 2. Loading vectors with magnitude less than 0.5 have been excluded from this plot. Green vectors indicate tumor properties while blue vectors indicate host tissue properties. Labels on each vector indicate the corresponding tumor property.