Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity
Fig 2
OEC and O2 offloading plot for various O2 carrying species used in the simulations.
(A) The OEC is shown for human hemoglobin (hHb) in human RBCs, mouse hemoglobin (mHb) in mouse RBCs, 30:1 R-State PolyhHb, and 35:1 T-State PolyhHb. (B) The O2 offloading plot as a function of the pO2 is shown for the same species. Approximate pO2 regions for arterial and venous blood under normoxic conditions have been included on this graph for reference.