Relations between large-scale brain connectivity and effects of regional stimulation depend on collective dynamical state
Fig 9
Relationships between phase-locking modulations and the structural or functional connectivity of the stimulated site vary with working point.
(A) Difference Δrs in the strength of the correlation between the average absolute baseline band PLV changes and structural (
) or functional (
) node strength, plotted as a function of the baseline drive
for a coupling C = 2.5. The difference is defined such that when the curve is positive, overall coherence modulations exhibit a stronger correlation with functional rather than structural strength. The arrows mark the locations of the different working points studied in detail in the main or SI Text. (B) A schematic summarizing how structural sstruc or functional sfunc strength are related to either baseline or excited band PLV changes for different dynamical regimes. As the background drive varies from low (WP1) to medium (WP2) to high (WP3), the oscillatory state of the system changes, and so does the association of different phase-locking modulations to structural or functional network properties.