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Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease

Fig 2

MAC-mediated hemolysis.

Percent hemolysis displayed against the number of MACs per cell (module 3). Data (circles) of human complement-mediated lysis experiments on sheep erythrocytes were obtained from [48] (S3 Appendix). The data was fitted with the sigmoid model of Eq 1 (line), with γ = 1.60 and MAC50 = 1.15 MAC/cell.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008139.g002