Vector genetics, insecticide resistance and gene drives: An agent-based modeling approach to evaluate malaria transmission and elimination
Fig 1
Representative genomes of cohorts or individual mosquitoes within EMOD.
The model supports the inheritance of traits from parents (a), random mutations of alleles (b), and definitions of phenotypic traits associated with a combination of genes or alleles, that are expressed only when those combinations are present (c). Inheritance of genes is modeled as a Mendelian process, and combinations of alleles can be mapped to combinations of traits via a many-to-many mapping.