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Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis

Fig 16

Overview of pharmacodynamic model.

Description of the integrated pharmacodynamic (PD) model for each compartment of the simulation model, incorporating bacterial growth, death, exchange with other compartments, bacterial drug resistance, and killing by immune system effects and active drug concentrations.

Fig 16

doi: https://doi.org/10.1371/journal.pcbi.1008107.g016