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Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis

Fig 10

Faster growth of drug-resistant bacterial strains due to incomplete drug therapy.

Comparison of growth of rifampin mono-resistant bacterial strain during treatment of TB infection, with standard drug therapy (2HREZ/4HR) vs. therapy excluding isoniazid. Based on simulation of 5000 patients. Infection occurs on day -180, and drug therapy is started on day 0.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1008107.g010