Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis
Fig 8
Population TB treatment outcome for different adherence patterns.
Comparison of median patient outcomes for treatment of TB infection, with standard drug therapy (2HREZ/4HR) at 100% adherence, 80% adherence randomly spaced throughout treatment, 80% during intensive or continuation phase and simulations from medication event monitoring system (MEMS) data. Based on simulation of 5000 patients. Infection occurs 180 days before treatment.