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A practical application of generative adversarial networks for RNA-seq analysis to predict the molecular progress of Alzheimer's disease

Fig 5

The false discovery rate and enrichment ratio value for downregulated pathways.

The false discovery rate (FDR) and enrichment ratio (ER) values for the selected pathways estimated by the gene list of each subset (Down, P4, P5, P6). Each pathway heatmap was estimated by averaging the transition curves of the genes belonging to the Down list. Genes were significantly downregulated for pathways involving the exocytosis of neurotransmitters with lower P5 FDR (the green box) and of specific synaptic functions with lower P6 FDR (the purple box).

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1008099.g005