Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes
Fig 9
Comparison of reported and estimated block percentages for IKr.
We consider the reported block percentages for 10 μM quinidine, 10 μM ivabradine, 30 μM ajmaline and 100 μM mexiletine from [11] and the block percentages estimated based on the IC50 values identified in the inversion procedure. Data are shown as the mean ± SEM. Data used in this figure can be found in S1 Data.