Template-based mapping of dynamic motifs in tissue morphogenesis
Fig 3
Visualization of detected motif appearances.
(A,B) Multiple sequence alignment of identified T1-transitions (A) and 5-cell rosettes (B). Snapshots in the rectangle correspond to the time points of cell rearrangement. Left arrows indicate that the sequence was temporally stretched by repeating the previous time point. (C) Left: Quantification of time-dependent frequencies of T1-transitions (red) and rosettes (green, blue) during the first 30 minutes of GBE, expressed as the number of events occurring in a size normalized tissue of 100 cells over a period of 1 minute. Right: a snapshot taken 16 minutes into GBE, showing the identified motifs, corresponding to cell groups at the transition time point. The image includes other cell groups undergoing rearrangements, but they are not at their transition points.