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Optimising efficacy of antibiotics against systemic infection by varying dosage quantities and times

Fig 4

Two-dose treatment regimen with the first dose d1 is taken at 2 h and the second dose 0.9-d1 at t2 h.

Host survival at 192 h is plotted against the size of the first dose d1: and the time of the second dose t2. Model runs = 10000.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008037.g004