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Assessing the performance of methods for copy number aberration detection from single-cell DNA sequencing data

Fig 4

Recall and precision of Ginkgo, HMMcopy, and CopyNumber as functions of the coverage.

The coverage is varied and the results are based on the (a) coarse-grained and (b) fine-grained analyses. The coverages are varied to mimic those produced by MALBAC, DOP-PCR, TnBC and Bulk sequencing.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008012.g004