Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus
Fig 4
Simulated biochemical cartilage degradation.
Predicted biochemical fixed charge density (FCD) losses in A) intact reference model and B) injury model. Biochemical degradation shown at time t = 4 d was simulated with 1 ng/ml of exogenous interleukin-1.