Physical constraints on early blastomere packings
Fig 4
Cell arrangements for repulsive ellipsoidal confinement.
Frequency of different cell arrangements for embryos with ellipsoidal repulsive confinement of varying aspect ratio (a/b) as the ratio of the shell volume and total cells volume varies (random divisions; τD/τM = 10; n = 104 simulation runs for each parameter set). Snapshots of non-equilibrium packing configurations for large shell volumes (Vs/Vc = 6) are shown on the right. Equilibrium (t = 8000τM) packing configurations for each aspect ratio and Vs/Vc = 1.52 are shown on the left (n = 200 simulation runs for each parameter set).