Physical constraints on early blastomere packings
Fig 3
Spherically confined cellular packings.
A, Frequency of different cell arrangements for embryos with spherical repulsive confinement as the ratio of the shell volume and total cells volume varies (random divisions; τD/τM = 10; n = 104 simulation runs for each parameter set). B, Histogram of the time to reach the equilibrium tetrahedral configuration (n = 103 simulation runs). C, Frequency of packing arrangements for embryos confined in a spherical repulsive shell (a/b = 1; Vs/Vc = 1.52), and both slow and fast divisions (τD/τM = 0.1, 10, respectively), different contact angles θ and both ordered and random division rules (n = 500 simulation runs for each parameter set).