Multiscale modeling of human cerebrovasculature: A hybrid approach using image-based geometry and a mathematical algorithm
Fig 11
Comparisons of statistical features for vascular structures of whole-pathways in the models reconstructed with actual and simplified brain hemisphere shapes.
(A) Hemisphere shapes for the actual model (orange) and simplified model (white), in which the major folds (cerebral sulcus) were artificially eliminated. (B) Reconstructed vessels in the simplified model for arteries (red) and veins (blue). (C) Relationships between the Euclidean distance L and path length C of the whole pathways between the root vertex and terminal ends. A linear regression line is also plotted for each model. (D,E) The relative frequencies of the path length C (D) and Euclidean distance (E) for the whole pathways. (F) Relative frequencies of the number of bifurcations on the whole pathways. (G) Relative frequencies of the index of whole-pathway tortuosity given as C/L − 1, where curves fitted using logarithmic normal distributions are shown.