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Realistic modeling of mesoscopic ephaptic coupling in the human brain

Fig 3

Realistic head model.

(A) Two views of the 3D volume conductor geometry, including volumes representing the scalp (yellow), skull (red), CSF (white), GM (light-grey) and WM (light blue). Models of electrodes, placed in the 10–10 EEG positions, are also included in the model (grey). The patch used to place dipoles in the multiple-source model (posterior wall of the post-central sulcus, on the right hemisphere) is displayed in red in the GM volume. It comprises a cortical surface of 5.30 cm2. The captions provide zoomed views of the cortical patch with the dipole sources. (B-G): Electric field magnitude (color bar in V/m) and vector field direction, and isosurfaces of the electrostatic potential (mV) in a sagittal slice passing through the middle of the right hemisphere post-central sulcus. First (B-D) and second (E-F) rows: dipole density per unit area of 0.5/1.0 nAm/mm2. Columns, from left to right: model with all dipole sources, model with single dipole in narrow region of the sulcus, model with single dipole in wide region of the sulcus. The location of the individual dipoles in the middle and right-most columns are shown as blue circles in Figs C and D. The sulcus is approximately 5.5 mm wide in its wide region and 1.8 mm wide in its narrow region. For the same reasons as highlighted in Fig 2, the colorscale of the E-field's magnitude is saturated to 0.1 V/m.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1007923.g003