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A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms

Fig 3

Ideal symport in a non-ideal (mixed) model.

The fluxes, J, of the driving ion and substrate of an example symporter model are plotted over a range of ion chemical potential differences. Note the 1:1 stoichiometry of the substrate to ion flux, indicating an ideal symporter with no leaks. The ion and substrate flux have been scaled by the maximum ion flux for visual clarity. Inset: kinetic pathway of the same symporter model at an ion chemical potential difference of −4kBT, as indicated by the vertical line.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1007884.g003