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A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms

Fig 1

Multiple mechanisms for ideal symport.

The four “ideal” kinetic pathways of a hypothetical symporter that transports substrate using the available free energy of the driving ion are shown. This state-space contains eight states, and symport models include at least six connecting transitions.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1007884.g001