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Ephaptic coupling in white matter fibre bundles modulates axonal transmission delays

Fig 8

Increasing the stimulus intensity, i.e. the number of spikes in a volley, decreases axonal transmission times and the latency of stimulus response.

A-C: Mean axonal delay with ephaptic coupling (solid) and without ephaptic coupling (dashed) for A: 1ms, B: 2ms, and C: 3ms stimulus duration. D-F: Standard deviation from the mean of axonal delay with ephaptic coupling (solid) and without ephaptic coupling (dashed) for D: 1ms, E: 2ms, and F: 3ms stimulus duration. Mean and standard deviation are computed from the distribution of delay times (cf. Fig 6D). G-I: Latency from stimulus onset to first maximum in neural mass model at G: 1ms, H: 2ms, and I: 3ms stimulus duration. Lines (shaded areas) indicate mean (1σ confidence interval) across 5 simulations. Colours indicate different bundle diameters.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1007858.g008