Mechanistic model of hormonal contraception
Fig 6
Model results (solid blue line) with edose = 40 pg/mL. In this simulation, LH has a small mid-cycle rise, but the large LH surge is significantly suppressed and ovulation does not occur indicating a contraceptive state, yet the hormone levels still vary during the cycle. For comparison, the normal cycling data are presented by a dashed-dotted magenta line.