Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth
Fig 4
Differences in the synthesis demand of enzyme cofactors and amino acids by aerobicity.
PCA analysis of all computed growth conditions reveals aerobic (filled points) and anaerobic (outlined points) growth conditions can be resolved by principal component 1. The protein biomass normalized micronutrient demand for L-histidine and NAD are shown next to their component 1 weighting. The two histograms demonstrate the clear separation in aerobicity-dependent demand of these micronutrients. A table of the principal component vector weightings is shown on the right.