Localized semi-nonnegative matrix factorization (LocaNMF) of widefield calcium imaging data
Fig 9
Brain areas show consistencies in their activity around task-related behavior, and in their ability to decode direction of licking activity.
A. The LocaNMF components of the trial-averaged activity of the right hand side primary visual cortex (VISp) under left and right visual stimulus, and of the primary somatosensory area, upper limb area (SSp-ul), left and right hand sides, before and after the lever grab. Each color indicates a different component in the same region. Standard error of the mean is shaded. B. The top demixed Principal Component of the trial-averaged activity of the right hand side primary somatosensory area, mouth (SSp-m1:R) and right hand side secondary motor cortex (MOs1:R) before and after the onset of a lick to the left or right spout (onset at time 0). Standard error of the mean is shaded. The activity around licking left or right in both regions is consistent across the two sessions. C. Decoding accuracy on held-out data for the direction of lick (Left vs. Right spout) using only components in a shaded brain region. A logistic decoder was used on the time courses on data from 0.67s before and 0.33s after the event (lick left or lick right).