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Localized semi-nonnegative matrix factorization (LocaNMF) of widefield calcium imaging data

Fig 4

Comparison with ROI analysis.

A. LocaNMF spatial components that are anchored to an Allen region show further specificity that may be lost if considering the average fluorescence in the Allen region as per an ROI analysis. B. The mean number of components recovered by LocaNMF. The bars are colored according to the cortical region they belong in, but note that there is one bar per subregion (ex. primary somatosensory cortex, right hand side upper limb). The dashed line at 1 signifies the number of components found with an ROI analysis.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1007791.g004