ASAP-SML: An antibody sequence analysis pipeline using statistical testing and machine learning
Fig 3
Area Under ROC Curves (AUC) for classification of MMP-targeting vs PDB-reference sets using SVM, random forest AdaBoost algorithms, while excluding biasing features and their associated features.
(a) AUC based on all included features, (b) AUC based on germline features, (c) AUC based on CDR canonical structure features, (d) AUC based on pI features, (e) AUC based on frequent positional motifs features, (f) AUC based on all features excluding all germline features and associated CDR canonical structure features.