Ion channel noise shapes the electrical activity of endocrine cells
Fig 5
The effect of cell size in the deterministic model.
(A) Event duration against cell size for the case where gBK = 0.5 nS at λ = 1. The spiking behaviour switches sharply to bursting at around λ = 1.35. Light shading: pure spiking; dark shading: pure bursting. (B) The critical BK conductance for switching between spiking and bursting as a function of the cell size. The blue curve (left axis) shows the total BK conductance within the cell (gBK), whereas the red curve (right axis) shows the BK conductance area density (gBK/4πR2).