Buffering and total calcium levels determine the presence of oscillatory regimes in cardiac cells
Fig 5
Time traces of the different calcium concentrations for different values of total calcium concentration, , and calsequestrin concentration set to zero (BSQ = 0).
After a transient, the system ends up in either a steady state which is excitatory at low levels of total calcium in the cell with observed low levels of calcium in the cytosol, in an oscillatory state with intermediate levels of total calcium in the cell, or in a state of high total levels of calcium in the cell with observed high cytosolic calcium levels.