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Buffering and total calcium levels determine the presence of oscillatory regimes in cardiac cells

Fig 1

a) RyR distribution in the cell. Each CaRU is formed by four simulation voxels, each one containing 9 RyRs. Thus, all CaRUs are formed by 36 RyRs. The CaRUs are distributed over the cell along the z-lines with a Gaussian distribution in both transversal and longitudinal axes. b) Each RyR follows a four state model, with stochastic transitions among the different states.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1007728.g001