An in-silico human cell model reveals the influence of spatial organization on RNA splicing
Fig 7
Formation of speckles in our simulations: A) splicing particles (U1 and U2 colored in yellow and orange, respectively) diffusing freely in the nucleus without speckle, B) Introduction of an imbalance on transition probabilities of splicing particles from the nucleus to speckles results in the localization of the splicing particles in the speckles shown as red-shaded regions.