An in-silico human cell model reveals the influence of spatial organization on RNA splicing
Fig 6
Our model predicts that the mRNA production decreases by a factor of two, above 0.05 μm.
An schematics shows a nuclear speckle in red and the distance of active genes on chromatin (curved line in grey) from the speckle periphery (d). Error bars represent the standard deviations. For each condition, 20 simulation replicates were performed.