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Inferring a simple mechanism for alpha-blocking by fitting a neural population model to EEG spectra

Fig 5

Forward calculation of the sensitivity of the alpha-rhythm to individual parameters.

Shown are calculations depicting the sensitivity of the alpha-rhythm to each of the nine state-distinct parameters. The initial state (green) is that of the best fit for EO Subject 25. Each parameter is then perturbed by +3% (red) or -3% (blue) of the plausible interval, keeping other parameters constant. We observe that perturbing pei changes the alpha rhythm amplitude most significantly, with a comparatively small change to the peak frequency. The same perturbations applied to pee had a similar type of effect, though reversed and to a smaller extent. Alpha band power is only weakly affected by γe or γi though they both control the frequency. We note in general that perturbations applied to the other parameters have significantly smaller effects than perturbations to pei.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1007662.g005