FilterDCA: Interpretable supervised contact prediction using inter-domain coevolution
Fig 12
The distributions of DCA scores of contacts and non-contacts.
For MSAs with Meff > 200 (Panel A) and 50 < Meff ≤ 200 (Panel B). Note that the enrichment of true positive predictions (contacts) is very high in the tail of large DCA scores. In fact, the majority of the pairs with DCA score larger than 0.3 corresponds to contacts. This is not the case for MSA with Meff < 50 (Panel C), where the two distributions completely overlap.