A stochastic model for simulating ribosome kinetics in vivo
Fig 5
Predicted codon decoding times and stalling frequency.
The average codon decoding times a stalling frequencies for each sense codon is calculated from the 215M individual decoding events that occur over the entire transcriptome in 1000s of simulation time. Blue and red bars indicate the T10 and T10a transcriptomes, respectively. Stalling events are computed as the frequency of ribosome stalling that occurs at the given codon.