A stochastic model for simulating ribosome kinetics in vivo
Fig 3
Peptide chain elongation rates at different E. coli growth rates.
The peptide chain elongation rates (Cp) in amino acids per second are shown for the simulations at growth rates μ = 0.7,1.0, and 2.5 doublings per hour. Running averages of Cp over 1000 seperate protein syntheisis events are given by the red curves and reveal an average peptide chain elongation of Cp = 15,18, and 21 amino acids per second for μ = 0.7,1.0, and 2.5 doublings per hour, respectively. All model predictions of the peptide elongation rates match experimental estimates of [24].