Modular analysis of the control of flagellar Ca2+-spike trains produced by CatSper and CaV channels in sea urchin sperm
Fig 10
CaV+BK (A) and CatSper+NHE (B) modules predict distinctive responses to manipulation of membrane potential.
The graphs show the numerical solutions of the indicated variables under the reference parameters as in Figs 4 and 6. The normal resting state is perturbed (in the absence of SAP, S = 0 nM) by setting the membrane potential to a higher value (V = 0 mV) at time t = 0 for a short period of 0.25 s (indicated by the two vertical dashed lines).