Regulatory context drives conservation of glycine riboswitch aptamers
Fig 1
Phylogenetic comparison of tandem riboswitches across Bacillaceae and Vibrionaceae.
A) 48 Bacillaceae and 37 Vibrionaceae tandem riboswitches were clustered based on aptamer sequence and structure across both aptamers of the riboswitch. After phylogenetic clustering, individual aptamers were colored based on the class of gene being regulated and the bacterial family of origin (Vibrionaceae TP are orange, Bacillaceae TP are purple, Bacillaceae GCV are green). Clusters have been labeled with the bacterial family and gene class being regulated. Bootstrap support values are displayed for 100 replicates when > = 70. B,C) Phylogenetic clustering of 48 tandem riboswitches, separated into aptamer-1 (B) and aptamer-2 (C), taken from the Bacillaceae family and colored according to class of gene being regulated (GCV are green, TP are purple). All trees are midpoint rooted.