Neuronal population model of globular bushy cells covering unit-to-unit variability
Fig 5
Dimensional stacking plots of the model parameter space.
A: Schematic presentation of dimensional stacking. Six-dimensional parameters are nested into three layers of two-dimensional spaces. Each rectangular cell of the outer layer, which corresponds to a specific combination of two parameters (number of inputs ME and adaptation strength SA, in this case), represents a middle layer (input amplitude AE and refractory period TR), which, in turn, consisted of the cells of the inner layer (coincidence window WE and adaptation time constant TA). B: Steady-state driven rates (7000 Hz pure tone, 70 dB SPL) of all 567,000 model instances shown with dimensional stacking. The spiking rate threshold of 150 (spikes/sec) is shown in black: instances that had lower spiking rates than this threshold (white-orange) were discarded, while instances with spiking rates equal to or higher than this threshold (dark to light blue) were adopted for further analyses. C: Degree of phase locking quantified as VS (350 Hz pure tone, 70 dB SPL) of all model instances. The VS threshold of 0.9 is shown in black: instances that showed lower VS than this threshold (white-orange) were discarded and those with higher (blue) were accepted. D: Steady-state driven rates of model instances that satisfied all the criteria of spontaneous activity, high-frequency sound-driven activity (rate and coefficient of variation) and low-frequency sound-driven activity (phase-locking and entrainment). E: Steady-state driven rates of model instances that satisfied all the criteria in D and additionally showed PLN-type PSTHs. In D and E, discarded model instances are shown in white, while accepted models are shown by the same color code as in B.