CBNA: A control theory based method for identifying coding and non-coding cancer drivers
Fig 3
Determining the directions of edges in the miRNA-TF-mRNA regulatory network.
In a miRNA-TF-mRNA regulatory network, miRNAs can regulate TFs and mRNAs, TFs can regulate miRNAs and mRNAs, TFs/mRNAs can regulate other TFs/mRNAs. This motif is adapted from the work of [66]. In addition, the databases used to filter out edges of the network are shown on arrows.