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Bioinformatics analysis of whole slide images reveals significant neighborhood preferences of tumor cells in Hodgkin lymphoma

Fig 8

Neighborhood of small, round cells in a low density area.

An exemplary subsection of an histological image with diagnosis MCcHL (ID 5722). The green points depict small, round cells (PC = 0) with a nearest neighbor of the same PC. The red points indicate all remaining PC. The clusters of small, round cells seem to be more often located in areas of low cell density (black arrows), whereas cell clusters of other PC seem to be more often in areas of higher cell density (white arrows).

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1007516.g008