The relative contributions of infectious and mitotic spread to HTLV-1 persistence
Fig 3
A and B respectively show the clone state space with and without an upper limit τ. Each box denotes the potential state of a given clone, i.e. the number of cells in that clone, with the corresponding propensity of each reaction at each state. π*(t) and δ denote the per-capita rates of infected cell proliferation and death respectively. Note there is no source inflow from frequency 0 to frequency 1. C and D show clone frequency probability distributions over time. Each curve shows the distribution of the probability that the given clone i contains xi cells at time t. At successive time points the curve broadens and either shifts to the right as the expected frequency of the clone increases (C), or shifts to the left as the expected frequency of the clone decreases (D).