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A computational study on the role of glutamate and NMDA receptors on cortical spreading depression using a multidomain electrodiffusion model

Fig 13

Dependence of velocity and duration on NMDAR and NaP during a spiral.

Calculated by finding the average value over the whole domain. The zero sections are regions where the spiral dies off due to a lack of propagation. Beyond the NMDAR level shown in the above graphs, the duration becomes too long preventing the spiral from recurring.

Fig 13

doi: https://doi.org/10.1371/journal.pcbi.1007455.g013