A computational study on the role of glutamate and NMDA receptors on cortical spreading depression using a multidomain electrodiffusion model
Fig 7
Different time profiles of neuronal membrane voltage and extracellular volume.
Each panel shows time courses from four different levels of NMDAR and NaP. For neuronal membrane voltage, as NMDAR permeability increases a secondary bump appears. It appears for even smaller levels of NMDAR, barely visible on the dashed line. The volume graph shows the large reduction in extracellular space.