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Novel comparison of evaluation metrics for gene ontology classifiers reveals drastic performance differences

Fig 7

Smin and SimGIC metrics.

We compared two versions of Smin, SimGIC and Jaccard each with Uniprot data. Performance was similar with all metrics, with the exception of GC Jacc which had a weaker correlation. Smin1 and SimGIC2 are slightly better methods. ADS signal is plotted on the x-axis and the evaluation metric, shown in headings, is plotted on the y-axis. We flipped the sign of the Smin metrics for consistency.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1007419.g007