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Benchmarking network algorithms for contextualizing genes of interest

Fig 3

Connectivity Map target prediction in the composite network or metabase signed+directed.

Performance was characterized by the ability of the algorithms to highly rank known targets of drugs. (A, top left) Fraction of datasets for which the algorithm appeared in the top five when ranked by fraction of drug targets recovered (B, top right) Fraction of datasets for which the algorithm appeared in the top five when ranked by AUROC.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1007403.g003