Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers
Fig 5
Computational evidence for existence of subtypes in human tumors.
A. Absolute proportion of each subtype in 81 human tumors as determined by CIBERSORT. The 81 tumors can then be sorted by hierarchical clustering, which finds four main groups of subtype patterns across tumors. B. Similar analysis in mouse PDX/CDX tumors from Drapkin et al. [18].