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Toxin production spontaneously becomes regulated by local cell density in evolving bacterial populations

Fig 3

Parameter conditions for the evolution of regulation.

The distribution of parameter values for simulations that yielded KRS-dynamics without regulation (n = 206) and those that yielded KRS-dynamics with regulation (n = 22). In simulations that resulted in the evolution of regulation, the spatial range of the cue and the response costs were lower, while the toxin production costs were higher. Results of 2-sided t-tests with Bonferroni-correction for multiple testing: **: p < 10−6, *: p < 10−3, n.s.: not significant.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1007333.g003